Uses of Dino-lite Digital Microscope for Detect Abnormal Scar Formation

Interactive platform for peer studying on biological and general microscopy. Dino-Lite microscope provide one of the most important platform in the field of studying biological sciences and general microscopy science. It allows students and lectures as the user to peer into the world of the cell, as well as discover the fascinating world of microscopic organisms and specimen with micron precision.

Detect Abnormal Scar Formation

detect abnormal scar formation

It was very hard and painful to detect skin diseases. The only tool was to perform a biopsy, where a skin tissue sample is extracted and sent for laboratory testing. The procedure is very inconvenient for patients, and an open wound also risks infections and needs suture which must be removed later.

Recently, a new technique was developed by a team led by Assistant Professor Xu Chenjie from Nanyang Technological University’s School of Chemical and Biomedical Engineering, nanoscience expert Professor Chad A. Mirkin from Northwestern University and Dr Amy S. Paller, Chair of Dermatology at Northwestern University Feinberg School of Medicine.

The new method is much more painless and allows doctor to take preventive measures earlier to help reduce the chances of serious scarring. Using new nanoparticles, the joint research team has shown in animals and human skin samples the potential to quickly and accurately predict whether a wound is likely to lead to excessive scarring as occurs in keloids and skin contractures.

Published last month in the Nature Biomedical Engineering journal, the new detection method uses thousands of nanoparticles called NanoFlares, which have DNA strands attached to their surfaces like a ball of spikes.

These nanoparticles are applied to closed wounds using a cream. After the nanoparticles have penetrated the skin cells for 24 hours, a handheld fluorescence microscope is used to look for signals given out by the nanoparticles’ interaction with target biomarkers inside the skin cells.

Using the Dino-Lite AM4115T-GFBW, when fluorescence signals are detected, they indicate abnormal scarring activity and preventive action can be taken to hopefully avoid heavier scarring.

Assistant Professor Xu Chenjie said: “When our bioengineered nanoparticles are applied on the skin, they will penetrate up to 2mm below the skin surface and enter scar cells.”

In other recently published or accepted peer-reviewed journal articles, such as in a SLAS Technology commentary, Dr Yeo further elaborates on the potential applications of NanoFlares for other skin diseases such as skin cancer, since the DNA sequences on the nanoparticles are interchangeable.

The team has filed a patent application based on this technology through NTU’s innovation and commercialisation arm, NTUitive, and will conduct a clinical trial by mid-2019.

 

References:

New nanoparticles help to detect serious wound

Nanoflares shine a light on formation of scar tissue

New method to detect abnormal scar formation


Uses of Dino-lite Digital Microscope for Art Conservation & Restoration

Over the past eight years, the Dino-Lite digital microscope has helped users around the world increase their productivity in a wide range of mundane to mission-critical applications. Due to its superior image quality, compact form factor, and ease-of-use, this product has quickly risen to a dominant position in the marketplace. From its initial success, the product line has expanded to include hundreds of models ( and accessories) to fulfill specific customer needs. As a result, the Dino-Lite microscope is now an indispensable tool in multiple market sectors, such as academics, manufacturing, quality control, healthcare, and education.

Art Conservation & Restoration

Art conservation is both an art and a science. The object of interest ranges from sculptures, ceramics, paper scroll (books, rolls, etc.), textiles and even architecture. Some of these could be performed in the lab, while others can only be done onsite. A microscope is a necessary tool in art conservation and restoration. They are used in non-destructive analysis and characterisation tests of the piece. Hence, the Dino-Lite digital microscope being small, light and portable is a great help for anyone in this field of work.

Dino-Lite digital microscope is a good support tool for art conservationists to restore and conserve objects and works of artists from the past. The portable digital microscope is held comfortably in your hand. It connects to a laptop via USB cable. The magnified image then appears on the screen through the DinoCapture 2.0 software. The alternative will be to look through an eyepiece of a stereo microscope.  The Dino-Lite digital microscopes comes with high magnification and built-in LED lights to illuminate the object being examined. It is a portable microscope that will be a useful visual aid to see details that cannot be seen by the naked eye. The small and light form factor makes it useful for analysing large sized artworks which can be difficult to reach with the traditional stereo microscope.

When used to inspect sculptures, ceramics or architecture, the digital microscope can also help to identify the different types of stone, such as marble or limestone. It can also be used to analyse the components in mortars. With the DinoCapture 2.0 software, users will also be able to easily take pictures or videos for documentation. Other analysis tools available on the software includes measurements of line, circle, diameter, radius, angle, centre distance and etc. As such, it is a neat tool for measuring the size of the sand granules in mortar. It can also be used as a diagnostic tool for identifying the source of the stone’s deterioration, helping to identify salts, pollution and biological growth. It can even locate historic tool marks and past conservation treatments. When looking at a stain at a higher magnification, as a user, you would be able to differentiate if the stains come from pollutions or fungus for example.

The special lighting models with UV or infrared lights can help the user to view hidden details found on the art piece. For instance, the AM4115-FKT comes with 780 nm infrared LED lighting and records high quality images at 1.3 Megapixels. This model can also magnify objects up to 200x. It is ideal to be used to analyse chemical and physical properties of paper. On the other hand, the AF4515T-FVW comes with a 400 nm UV light source. The UV light source is a good aid for revealing historical moisture and mould damage to a paper. These are not always visible to the naked eye. Areas of the paper which were previously in contact with water, where size and the products which cause fluorescence have been removed, appear darker under UV light. All this information can then be used to aid the decision making process of forming a suitable conservation treatment.

Art restoration and conservation is a process that needs to be carried out very carefully. Art restorers would normally need to clean the art objects with great care so as not to damage the last original paint coat. They would need to differentiate between dirt, excess paint and original paint layer. They would also need to determine the authenticity of the items by looking at the object structure. With microscopes that can magnify items at 200x magnification, Dino-Lite can help to analyse in detail visually the different materials used to produce the art.

National Galeri Indonesia using dino-lite

Dino-Lite being used to check a painting and projected on a wide TV screen.

The user will also find Dino-Lite USB microscope’s ability to capture images and videos, which can be annotated, to be very useful for documenting historical art objects. The user would also have the flexibility to select the medium they wish to view the art with. Dino-Lite digital microscopes can display images on TV screens, PC monitors, laptops and even Android devices. Art professionals can easily observe the work without any contact with the microscope’s ability to view items at a distance with the long working distance models of Dino-Lite.

Some might argue that without digital microscopes, conservators in the field can still turn to handheld loupes for analysis. However, the magnification powers of such loupes can only go up to about 30x. At the end of the day, the samples viewed will still need to be taken to a laboratory for analysis. Whereas the Dino-Lite USB microscope offers magnification of up to 250x. Analysis can be done immediately when you are on field. In the case of stone conservators, after looking at the stone with the Dino-Lite digital microscope, they can take samples, for example, of each kind of biological growth and bring them back to the lab for further analysis. The information can then be used to decide treatment plans for the long-term care and conservation of the stone monuments and buildings.

The Dino-Lite digital microscopes have time and again proven to itself to be a cost-effective tool. Coupled with the free DinoCapture 2.0 software, it will greatly help to speed up the analytical process in conservation studies of many different types of materials.

 

References
1. Nichols, E. (2016, December 14). Under the microscope – preliminary investigations of the changi archive conservation research project. Retrieved April 14, 2021, from https://specialcollections-blog.lib.cam.ac.uk/?p=13554
2. Lee, C. (2020, November 02). Conservation tools: The usb digital microscope. Retrieved April 14, 2021, from https://blogs.getty.edu/iris/conservation-tools-the-usb-digital-microscope/


Uses of Dino-lite Digital Microscope for Ophthalmology

Ophthalmology

ophthalmology

Ophthalmology is the field of medicine that deals with the anatomy, functions, and diseases of the eye. This includes the diagnosis and treatment of disorders of the eye. An ophthalmologist is a physician who specializes in ophthalmology. The credentials include a degree in medicine, followed by an additional four to five years of residency training in ophthalmology. Residency training programs for ophthalmology may require a one-year internship with training in internal medicine, pediatrics, or general surgery. Additional specialty training (or fellowship) may be sought in a particular aspect of eye pathology. Ophthalmologists are allowed to prescribe medications to treat eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists may participate in academic research on the diagnosis and treatment of eye disorders.

Improved View

Dino-Lite digital microscopes can help ophthalmologists when you are doing iris examinations. The AM4113-RUT is one of the many models by Dino-Lite that is suitable for such work. It is a USB microscope which is used by connecting it to a computer. The main benefit of using digital microscopes is improved view. As a user, you would be able to examine the iris through a large screen monitor instead of hunching over patients. Ophthalmologists typically must hunch to get a close examination of the patients’ iris through oculars. The AM4113-RUT enables you to sit comfortably throughout the day as you are examining patients one after another. Extended periods of bending over oculars to examine multiple patients in a day may create a cumulative strain on your back. Over time, it can be damaging to your back and cervical spine. The traditional approach takes a lot of wear and tear on your bodies. Studies show that between 30% and 50% of ophthalmologist end up with cervical neck pain or herniated discs due to the way you must position your bodies to view the eye with a traditional microscope.

Using Dino-Lite

Ease of Use

The AM4113-RUT is easy to use. It is very much like the other Dino-Lite models where you merely use a single scroll to magnify and focus all at once. Your movements and hand placement may be different than using oculars. Most ophthalmologists are used to resting your head against the microscope as you look through the oculars. With the AM4113-RUT, you would no longer need to rest your head against the oculars of the microscope. It is a minor change that one can easily adapt to. Rest assured that the learning curve of using such a digital microscope is not steep. As a user, you would not require a long time to get accustomed to the Dino-Lite as it is as simple as viewing an image on the screen.

Dino-Eye with Measurement

Data Collection

USB models of Dino-Lite digital microscopes are used with the DinoCapture 2.0 software. The application exists to support ease of documentation of your iris examination. You would be able to take pictures or videos by using the MicroTouch function. On the AM4113-RUT, there is a touch sensitive trigger for taking pictures and videos. Upon a single click, a picture is taken and automatically saved on your computer. All recent videos and images taken can be viewed on the left-hand bar of the DinoCapture 2.0 software. You can view the information seamlessly without interruptions during the examination. This is also a neat software for organizing and filing of patients’ iris examination images. It is easy to transfer images and videos from the DinoCapture 2.0 as they are saved to a designated folder in your computer.  As you begin to use the digital microscope, you can get used to taking advantage of its capabilities. You will find an increase in efficiency as a benefit upon switching to the digital microscope. It will also greatly help you if you are seeking to file data in a “paperless” manner.

DinoCapture Interface

Communal Viewing

Anyone in the examination room — assistants, technicians, medical students — can watch the examinations on a monitor. As a result, it will help them to understand the patients’ situation better. If we compare it to the use oculars for examinations, only the person viewing through the microscope can get the complete picture. The others in the room will not be able to look at a monitor. The ability to see exactly what the doctor is seeing is an incredible advantage for teamwork overall. Everyone can better anticipate what is happening during the examination. Further, it also serves as a tool for resident education, fellow education, and medical student education because everyone is seeing the same thing at the same time.

ophthalmology 02

Increased Safety

In the COVID-19 pandemic, digital microscopes offer an additional barrier of safety for doctors and patients. Being able to examine patients through the monitors, and not through the oculars, allows the ophthalmologist to wear a full-face shield. There is a great safety advantage to having the ability to sit back and not hover directly over the patient’s face during examination. The ability to cover your face and eyes with a face shield is an important layer of protection, for both patients and doctors amid the pandemic. Information captured is also directly saved into the computer. You would not need to handle information on written copies. You would be able to access the images again by going through them in the computer. As a result, you would be less prone to error. Data that is captured goes straight from the digital microscope directly to the computer. It increases efficiency and is better for patient safety. When examining multiple patients, you would want to do it with as little room for error as possible. Digital microscopes close that gap quite a bit.


Uses of Dino-lite Digital Microscope for Nail Capillary

Nail Capillary

dino-lite-for-nail-capillary

A capillary is a small blood vessel from 5-10 micrometres in diameter. They are the smallest blood vessels in the body: they convey blood between the arterioles and venules. Physician could diagnose various kinds pf disease by checking up the nail capillary.

Dino-Lite Nail Microcirculation Scope has a magnification of 500x and can examine the capillary with magnified clarity and digitally record the image for diagnostic and other purposes.


watch authentication using dino-lite-2

Uses of Dino-lite Digital Microscope for Watch Authentication

Watch Authentication

watch authentication using dino-lite-2

With a fast-growing tech-savvy population of watch enthusiasts, the purchase of luxury timepieces over the internet can be carried out with much ease and convenience. Any watch from any corner of the world could be purchased and couriered to your doorstep in a matter of days. Unfortunately, this ease and convenience has also led to a proliferation of replicas and outright fakes being spawned off as real deals, leading to substantial losses as a result.

watch authentication using dino-litewatch authentication using dino-lite-3watch authentication using dino-lite-2watch authentication using dino-lite-1

ino-Lite digital microscope is a handy and simple tool which can be used to ensure the provenance and authenticity of a watch. With the IP camera feature, you no longer need to take the trouble, time, and effort to personally travel to the source and personally inspect the watch. This can all be done remotely over the Internet. We are proud to be supporting digitalization of watch authentication today. To lessen the uncertainties, some watch brands have even developed ways to establish the identity of their watches by relying on blockchain, the database technology used for tamper-proof storage of digital information that is accessible to all. The high-quality images captured by Dino-Lite digital microscopes can be used for watch authenticators to verify the watch.


Uses of Dino-lite Digital Microscope for Watchmaking / Repair

Watchmaking / Repair

luxury watch inspect

A good watch can consist of dozens, or even hundreds of mini parts. All parts need to be put together to make the watch work. Although most watches are now factory made, a watchmaker still needed to repair watches. Repairing watches can be a very intricate job to do, because of the number of tiny parts a watch has. Watchmaker will need to use magnifying tools that have polarized lighting. It helps provide uniform illumination to bring out more surface detail with minimal glare.


Uses of Dino-lite Digital Microscope for Diamond Examination

Diamond Examination

dino-lite-for-diamon-examination

Diamonds certainly come in a variety of sizes, colors, and shapes. All diamonds possess intricate combinations of characteristics that make them unique. Most diamonds have minor inclusions and it is these internal markings that are very valuable in identifying your diamond, because there are no two diamonds that have inclusions in exactly the same places.

The other things that you look for are abrasions on the surface, nicks or cavities or cracks that may affect the structural integrity of the diamond. To examine diamond’s clarity, you will need some magnification tool. Dino-Lite Microscope for jewelers has the ability to examine stones, inspect jewelry for repairs, assist in appraisals and make imaging inventory fast and easy.


dino-lite-for-marking-inspection

Uses of Dino-lite Digital Microscope for Marking Inspection

Marking Inspection

dino-lite-for-marking-inspection

Dino-Lite is cleverly designed for industrial quality control engineers to perform visual inspections at the microscopic level. Many of the features will enable you to work with ease. The Dino-Lite models with the polarizer, for instance, is widely used in industrial inspections to reduce glare from highly reflective surfaces. The Dino-Lite microscopes with UV leds enables the user to detect minute scratches which cannot be easily detected by the naked eye.